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Herbal Supplements and the Brain: Understanding Their Health Benefits and Hazards

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Product Author Bios

S.J. Enna (Kansas City, KS) is Professor at University of Kansas Medical Center's Department of Molecular and Cellular Physiology. He has made significant contributions in defining pharmacological and biochemical properties of neurotransmitter receptors, especially those for GABA. Dr. Enna's research is described in 200+ published research reports, reviews, and book chapters.

 

Stata Norton (Kansas City, KS), Emeritus Professor at the University of Kansas Medical Center's Department of Pharmacology, Toxicology and Therapeutics has published extensively in Molecular Interventions and elsewhere.

Today, many manufacturers of plant-based "neuroceuticals" claim their products can offer powerful benefits in brain function. However, the US government does not require these manufacturers to demonstrate their products’ effectiveness, leaving it difficult for consumers and health professionals to make decisions about the benefits and risks. In Herbal Supplements and the Brain: Understanding their Health Benefits and Hazards, two leading researchers provide this crucial information in clear language any intelligent reader can understand and use. They begin by introducing the fundamental principles of pharmacology, explaining how drugs and natural products can affect the body’s organs and organ systems. Using examples, they show how to determine whether an ingested substance can enter the bloodstream and reach its target at a concentration sufficient to have an effect. They also explain how natural products may influence blood levels of other substances, and discuss whether such interactions may diminish the effectiveness of prescription medications or alter normal body chemistry. Throughout, the authors emphasize factors relating especially to neuroceuticals and the brain. Individual chapters are devoted to nutritional supplements which promise to enhance memory, relieve pain, safely promote sleep, and aid in the treatment of depression or anxiety. Specifically, readers will find research-based coverage of Ginkgo biloba; St. John’s Wort; Valerian; Lemon Balm; Kava; Lavender; Kudzu, Daffodil, Passion Flower, and Camellia Tea and other caffeinated beverages.

Customer Reviews

9 of 11 people found the following review helpful
3.0 out of 5 stars Not what I was expecting., May 31, 2012
By 
Sharon Isch (Washington, DC USA) - See all my reviews
(VINE VOICE)    (TOP 500 REVIEWER)    (REAL NAME)   
This review is from: Herbal Supplements and the Brain: Understanding Their Health Benefits and Hazards (FT Press Science) (Hardcover)
Customer review from the Amazon Vine™ Program (What's this?)
In their preface the authors say "the primary audience for this book is consumers interested in determining the value of herbal products purported to influence brain function." The jacket copy says it is "written in plain English and brings together all the scientific information you need to decide for yourself how the use of plant products affect the brain to enhance memory, relieve pain, promote sleep and treat depression or anxiety." That's a pretty tall order for a book of 193 pages (plus 40 pages of source notes) that covers only 10 supplements. "Written in plain English" is NOT how this reader would describe it. (I noticed that those quoted as describing it as such appear to be pharmacology professors.) This book reads to me much more like something written for an audience of scientists, academics and students of pharmacology.

The 10 herbal supplements discussed in this book are: Ginkgo, St. Johns Wort, Valerian, Lemon Balm, Kava, Lavender, Kudzu, Daffodil, Passion... Read more
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4 of 4 people found the following review helpful
3.0 out of 5 stars Its Ok, July 23, 2012
By 
Jerry Palmerino Jr (United States) - See all my reviews
(VINE VOICE)   
This review is from: Herbal Supplements and the Brain: Understanding Their Health Benefits and Hazards (FT Press Science) (Hardcover)
Customer review from the Amazon Vine™ Program (What's this?)
I was excited to acquire this book. Unfortunately, I wan't too excited after reading it.

It is a very limited view of supplements for the brain. Having seen the film "Limitless", I started researching nootropics on the internet. So much more information is available on the web, that my knowledge already exceeded what was contained within the pages of this book. Granted, "Limitless" is fantasy, but there are supplements that boost your mental abilities...One very common one is caffeine.

This book covers Ginko, St. John's Wort, Valerian, Lemon Balm, Kava, Lavender, Kudzu, Daffodil, Passion Flower, Coffee, Tea, and Cocoa. Most of the above are available as teas in your local grocery store and most of these are stress reducers/calming agents.

Perhaps the limitations of this book are due to its focus on "herbal" supplements. I am not sure why though, because most nootropics I know of are plant-based or vitamins. Some, though, are synthetic compounds... Read more
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2 of 2 people found the following review helpful
4.0 out of 5 stars Well-researched and informative look at the top brain supplements, October 9, 2012
By 
D. A. Ross (Minneapolis, Minnesota USA) - See all my reviews
(VINE VOICE)    (REAL NAME)   
This review is from: Herbal Supplements and the Brain: Understanding Their Health Benefits and Hazards (FT Press Science) (Hardcover)
Customer review from the Amazon Vine™ Program (What's this?)
I love my herbs and I love my brain, so the book Herbal Supplements and the Brain: Understanding Their Health Benefits and Hazards, had immediate appeal to me. Authors S.J. Enna and Stata Norton do a remarkable job providing ample background into ten different herbal supplements and their effects on the brain, as well as presenting the information in a thorough, if not academic, fashion. As noted, the herbs covered in this book are: Gingko, St. John's Wort, Valerian, Lemon Balm, Kava, Lavender, Kudzu, Daffodil, Passion Flower, and the triumvirate of Coffee, Tea and Cocoa.

The book starts with a surprisingly fascinating account of herbal use throughout history which, if history does not appeal to you, may be skimmed or skipped altogether, if one so desires. The next two chapters cover pharmacology, and the biology and inner-workings of the brain itself. Each subsequent chapter then focuses on one herb, and is broken down into the following sections:

* Botany... Read more
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Online Sample Chapter

Herbal Supplements and the Brain: Understanding Their Health Benefits and Hazards

Table of Contents

Preface     xvi

Chapter 1 The Gifts of Eden     1

Chapter 2 Transforming Plants into Gold     7

Prehistoric Evidence     8

Early Documentation     9

Western Culture     11

Alchemy     13

Chemistry     15

Chapter 3 Thinking Like a Pharmacologist     17

The Origins of Pharmacology     19

Pharmacodynamics     21

Pharmacokinetics     24

In Vitro and In Vivo Studies     27

Pharmacology and Herbal Supplements     27

Herbal Supplement Pharmacology Checklist     28

Chapter 4 The Brain as a Drug Target     33

The Human Brain     36

Chemical Neurotransmission     39

Neurotransmitter Systems     41

Behavioral Assays     45

Clinical Studies     49

Chapter 5 Ginkgo (Ginkgo biloba)     53

Botany     55

Therapeutic Uses     55

Constituents     57

Pharmacokinetics     59

Pharmacodynamics     61

Adverse Effects     65

Pharmacological Perspective     66

Chapter 6 St. John’s Wort (Hypericum perforatum)     67

Botany     69

Therapeutic Uses     70

Constituents     71

Pharmacokinetics     74

Pharmacodynamics     75

Adverse Effects     80

Pharmacological Perspective     81

Chapter 7 Valerian (Valeriana officinalis)     83

Botany     84

Therapeutic Uses     85

Constituents     86

Pharmacokinetics     88

Pharmacodynamics     90

Adverse Effects     93

Pharmacological Perspective     94

Chapter 8 Lemon Balm (Melissa officinalis)     97

Botany     98

Therapeutic Uses     99

Constituents     99

Pharmacokinetics     100

Pharmacodynamics     102

Adverse Effects     106

Pharmacological Perspective     106

Chapter 9 Kava (Piper methysticum)     109

Botany     110

Therapeutic Uses     111

Constituents     112

Pharmacokinetics     112

Pharmacodynamics     114

Adverse Effects     118

Pharmacological Perspective     120

Chapter 10 Lavender (Lavandula angustifolia)     123

Botany     124

Therapeutic Uses     125

Constituents     126

Pharmacokinetics     127

Pharmacodynamics     129

Adverse Effects     134

Pharmacological Perspective     135

Chapter 11 Kudzu (Pueraria lobata)     137

Botany     138

Therapeutic Uses     139

Constituents     140

Pharmacokinetics     141

Pharmacodynamics     143

Adverse Effects     146

Pharmacological Perspective     147

Chapter 12 Daffodil (Narcissus pseudonarcissus)     149

Botany     151

Therapeutic Uses     152

Constituents     153

Pharmacokinetics     154

Pharmacodynamics     155

Adverse Effects     158

Pharmacological Perspective     159

Chapter 13 Passion Flower (Passiflora incarnata)     161

Botany     162

Therapeutic Uses     163

Constituents     164

Pharmacokinetics     166

Pharmacodynamics     168

Adverse Effects     173

Pharmacological Perspective     173

Chapter 14 Coffee, Tea, and Cocoa     175

Botany     177

Therapeutic Uses     178

Constituents     180

Pharmacokinetics     182

Pharmacodynamics     184

Adverse Effects     186

Pharmacological Perspective     187

Chapter 15 Epilogue     189

Endnotes     195

Index     237

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